INCLUSION BODIES FROM NEWCASTLE DISEASE VIRUS IN HeLa CELLS
نویسندگان
چکیده
منابع مشابه
Presence of Viral Antigen in Inclusion Bodies Formed in Ehrlich Ascites Tumor Cells Injected with Newcastle Disease Virus †
Prince and Ginsberg,1 using the fluorescent antibody technique of Coons to study the interaction between Newcastle disease virus and Ehrlich ascites tumor (EAT) cells, showed that following in vitro infection and subsequent incubation in vivo there occurred hyperplasia of the EAT cells and a concomitant increase in viral antigen within the cytoplasm of the infected cells. They were able to show...
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The ability of NDV-infected HeLa cells to synthesize DNA, protein, and RNA was investigated by measuring the incorporation of tritiated precursors into these substances at intervals after infection of cells with a virus/cell multiplicity of 500:1. A significant decrease in incorporation of precursors into DNA and protein was first observed at 3(1/4) hours after infection. By 4(1/2) hours, an 80...
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BACKGROUND/AIMS Newcastle disease virus (NDV) is an avian paramyxovirus that has gained a lot of interest in cancer viro-therapeutic applications because of its ability to selectively induce apoptosis in human cancer cells. However, the underlying mechanisms by which NDV induces apoptosis in human cancer cells are still not entirely understood. METHODS In this study we examined the effect of ...
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In order to adapt LaSota strain of Newcastle disease virus (NDV) on chick embryo fibroblast (CEF) cells, 0.1 ml from LaSota vaccine produced in Razi vaccine and serum research institute inoculated to the CEF cells and was passaged five times in the CEF grown in Eagle’s minimum essential medium (MEM). First to third passages were blind but in fourth passage cytopathic effect of virus was observe...
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Newcastle disease virus (NDV) California strain reportedly grows poorly in L cells but replicates very well in chicken embryo cells. NDV-infected L cell cultures show a characteristic virus growth curve with respect to uridine incorporation, but plaque assays of the virus produced 24 h postinfection (PI) show no infectious particles when assayed on L cell monolayers and only a very low titer on...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1961
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.82.1.151-152.1961