Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
نویسندگان
چکیده
منابع مشابه
In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction.
The use of stem-cell therapy to treat retinal degeneration holds great promise. However, definitive methods of retinal differentiation that do not depend on recombinant proteins produced in animal or Escherichia coli cells have not been devised. Here, we report a defined culture method using low-molecular-mass compounds that induce differentiation of human embryonic stem (ES) cells and induced ...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2008
ISSN: 1087-0156,1546-1696
DOI: 10.1038/nbt1418