Inflammation modulates fibronectin isoform expression in colonic lamina propria fibroblasts (CLPF)
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چکیده
منابع مشابه
Identification of Lymphatics within the Colonic Lamina Propria in Inflammation and Neoplasia Using the Monoclonal Antibody D2-40
CONTEXT Lymphatic vessels are believed to be absent in the colon above the level of the mucularis mucosae. However, in our experience, lymphatic vessels are sometimes identifiable within the lamina propria in the setting of inflammation and neoplasia. OBJECTIVE We sought to assess the presence of lymphatics within the colonic lamina propria in neoplastic and inflammatory conditions using the ...
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OBJECTIVE To investigate the role of adrenoceptor subtypes in regulating the spontaneous contractile activity of the inner lining of the urinary bladder (urothelium/lamina propria). MATERIALS AND METHODS The responses of isolated strips of porcine urothelium/lamina propria to noradrenaline, phenylephrine, and isoprenaline were obtained in the absence and presence of receptor subtype-selective...
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Multinucleated stromal giant cells were seen in the colonic mucosa in biopsy specimens from two patients with long-standing quiescent ulcerative colitis. Similar cells have been described at other sites associated with chronic inflammation, including the lower female genital tract, bladder and anus. The immunophenotype of the cells in the colonic mucosa suggested that they had originated from f...
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BACKGROUND A frequent complication of Crohn's disease (CD) is the formation of strictures and stenoses. Strictures are characterized by a fibrosis of the bowel wall, induced by abnormal wound healing. Functional changes of colonic lamina propria fibroblasts (CLPF) reflected by increased proliferation and collagen synthesis, increased contractility or reduced migratory potential, indicate a chan...
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Dysregulation of TNF-α in lamina propria macrophages (LPM) is a feature of inflammatory bowel diseases (IBD). LPS-Induced-TNF-Alpha-Factor (LITAF) is a transcription factor that mediates TNF-α expression. To determine whether LITAF participates in the mediation of TNF-α expression in acutely inflamed colonic tissues, we first established the TNBS-induced colonic inflammation model in C57BL/6 mi...
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ژورنال
عنوان ژورنال: International Journal of Colorectal Disease
سال: 2008
ISSN: 0179-1958,1432-1262
DOI: 10.1007/s00384-008-0523-z