Inhibition of Bacterial Deamination by Nitrofuran Derivatives
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There is a need to identify novel scaffolds and targets to develop new antibiotics. Methylene blue is a phenothiazine derivative, and it has been shown to possess anti-malarial and anti-trypanosomal activities. Here, we show that different phenothiazine derivatives and pyronine G inhibited the activities of three structurally different bacterial RNase P RNAs (RPRs), including that from Mycobact...
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ژورنال
عنوان ژورنال: NIPPON SUISAN GAKKAISHI
سال: 1953
ISSN: 1349-998X,0021-5392
DOI: 10.2331/suisan.19.688