Inhibition of cathepsin D by synthetic oligopeptides.
نویسندگان
چکیده
منابع مشابه
Inhibition of cathepsin D by synthetic oligopeptides.
A number of synthetic oligopeptides with the COOH terminus D-amino acid situated third from the potentially cleavable phenylalanyl-phenylalanyl bond, typified by < Glu-D-Phe-Pro-Phe-Phe-Val-D-Trp (Peptide VI) were shown to be potent competitive inhibitors of cathepsin D and pepsin. Peptide VI, which forms an equimolar nonproductive enzyme l inhibitor complex, inhibited the hydrolysis of methyl[...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1979
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)86398-6