Inhibition of glucose formation from fructose by phenformin in perfused guinea pig livers
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Selective inhibition by antiflamrnin-2 of thromboxane B2 release from isolated and perfused guinea-pig lung
Antiflammin-2 (AF2) is a nonapeptide corresponding to the amino acid residues 246-254 of lipocortin-1 showing anti-inflammatory activity both in vitro and in vivo. The effect of AF2 on the thromboxane B(2) (TXB(2)) and histamine release from isolated and perfused guinea-pig lungs has been studied. AF-2 (10-100 nM) inhibited leukotriene C(4)- (LTC(4)) (3 ng) and antigen-induced (ovalbumin, 1 mg)...
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the main purpose of this research was to:1.develop a coking model for thermal cracking of naphtha.2.study coke inhibition methods using different coke inhibitors.developing a coking model in naphtha cracking reactors requires a suitable model of the thermal cracking reactor based on a reliable kinetic model.to obtain reliable results all these models shall be solved simultaneously.for this pu...
15 صفحه اولEthanol predominantly constricts pre-sinusoids of isolated perfused livers of rat, guinea pig and mouse.
AIMS Ethanol constricts hepatic vessels of isolated perfused livers of rats, but not dogs. However, it is not known whether ethanol constricts or dilates the hepatic vessels in other species such as guinea pigs and mice. In addition, the sites of hepatic venoconstriction induced by ethanol were not known in rat livers. We therefore studied the effects of ethanol on the segmental hepatic vascula...
متن کاملIsolated Perfused Guinea Pig and Rat Hearts
Adenosine is known to cause atrioventricular block by slowing conduction through the atrioventricular node, thereby lengthening the atria to His (A-H) interval. To test the hypothesis that the increase in atrioventricular conduction delay produced by adenosine is mediated at an extracellular site, the efficacy of nucleoside transport inhibitors in preventing cellular adenosine uptake was correl...
متن کاملCyclooxygenase inhibition aggravates ischemia-reperfusion injury in the perfused guinea pig heart: involvement of isoprostanes.
OBJECTIVES Postischemic contractile dysfunction in the heart may be due, in part, to isoprostanes, thought to accumulate during myocardial reperfusion. This study tested whether cyclooxygenase (COX) inhibitors increase the amount of isoprostanes and, consequently, lead to deterioration of postischemic heart function. BACKGROUND Isoprostanes are bioactive prostaglandin-like compounds that are ...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1973
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf01230698