Inhibition of lens protein glycation and aldose reductase activity using Aqueous extract of Morinda Citrifolia and Ocimum Sanctum in Glucose induced diabetic cataract

Diabetes mellitus is a chronic disorder characterized by persistent elevated blood glucose level in the body which leads to various secondary complications like cataract. The understanding of mechanisms exerts its toxicity utmost importance for rational pharmacological interventions treat diabetic Plants have always been an exemplary source drugs and many currently available derived directly or indirectly from them. aim present study was explore local antiglycation anticataract potential M. citrifolia O. sanctum goat lenses using induced cataract model. A total 120 were divided into four groups 30 each viz. Normal Control, Experimental cataract, + Extract Morinda (0.25%), Ocimum (0.25%). Extent protein glycation activity aldose reductase measured lens homogenates. cataractous showed increased levels both as well activity. However, treated with significant decreased