Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure
نویسندگان
چکیده
منابع مشابه
Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure.
Hereditary spastic paraplegias are a clinically and genetically heterogeneous group of gait disorders. Their pathological hallmark is a length-dependent distal axonopathy of nerve fibers in the corticospinal tract. Involvement of other neurons can cause additional neurological symptoms, which define a diverse set of complex hereditary spastic paraplegias. We present two siblings who have the un...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2013
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1217197110