Insulin Affects Glucose Uptake by Muscle and Mammary Tissues of Lactating Ewes
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چکیده
منابع مشابه
Substrate selection and oxygen uptake by the lactating mammary gland.
Toutes les proteines et tout le lactose, et environ 50% des acides gras des lipides du lait sont synthdtisks par les cellules CpithCliales de la gland mammaire. Au pic de la lactation, il y a une demande CnergCtique ClevCe auprbs de ces cellules pour fournir les substrats circulants (glucose, acides gras, corps cCtoniques, triacylglycCrols et acides aminks), pour les rCactions de biosynthbse, e...
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During lactation, mineral and nutrient requirements increase dramatically, particularly those for Ca and glucose. In contrast to monogastric species, in ruminants, it is rather unclear to which extend this physiological change due to increased demand for milk production is accompanied by functional adaptations of the gastrointestinal tract (GIT). Therefore, we investigated potential modulations...
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Kinetic properties and substrate specificity of the lysine transport system in porcine mammary gland were studied using mammary tissue explants from nine lactating sows. Sodium dependence of lysine uptake was determined by replacing sodium in the medium with choline. Kinetic parameters of lysine uptake were determined using lysine concentrations from 5 microM to 5.12 mM. Competition of lysine u...
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1. Utilization of 5mM-glucose by slices of lactating mammary gland was decreased 33% on addition of acetoacetate (2mM) to the incubation medium. This inhibition was accompanied by increases in the intracellular concentrations of citrate and glucose 6-phosphate. 2. In the presence of acetoacetates the accumulation of pyruvate in the medium approximately doubled. 3. Insulin completely reversed th...
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The hypothesis of this investigation was that insulin and muscle contraction, by increasing the rate of skeletal muscle glucose transport, would bias control so that glucose delivery to the sarcolemma (and t tubule) and phosphorylation of glucose intracellularly would exert more influence over glucose uptake. Because of the substantial increases in blood flow (and hence glucose delivery) that a...
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ژورنال
عنوان ژورنال: Australian Journal of Biological Sciences
سال: 1988
ISSN: 0004-9417
DOI: 10.1071/bi9880453