Integration of Omics Tools for Understanding the Fish Immune Response Due to Microbial Challenge

Nowadays, fish production through aquaculture and wild capture is escalating due to the higher protein demand for human consumption. Thus, needs products be improved in scale quality are becoming increasingly important meet nutrition requirements. The negative impacts caused by pathogens infection both hatchery grow-out ponds, have resulted low productivity economic losses farmers. Therefore, a systematic study exploring relevant omics datasets systems biology approach will enable scientist describe complexity characteristics of interactions host-pathogen network, leading identifying new targets or biomarkers diseases bacteria, viruses, parasites. use different approaches emerging technologies as powerful tool obtaining knowledge sustainable has been applied many researchers over years. In this paper, several used assess immune response were reviewed. A brief description provided applicable aquacultures, such genomics, transcriptomics, proteomics, metabolomics. Each contributes develop better treatment prevention strategies overcome disease microbial infections. genomics transcriptomics analysis, their parallel involving gene expression studies play role immune-related genes host, infectious diseases. While proteomics metabolomics approaches, these provide information on biomarker discovery understanding biosynthetic pathway during pathogen infection. Additionally, examples integrative analysis multi-omics tools required understand biological aquatic animals especially fish, also provided.