Interleukin 17F Level and Interferon Beta Response in Patients With Multiple Sclerosis

Interleukin-17A and Interleukin-17F mRNA Expressions in Peripheral Blood Mononuclear Cells of Patients with Multiple Sclerosis

Bakground: Multiple sclerosis (MS) is a CD4+ T cell-mediated autoimmune disease affecting the central nervous system (CNS). It was previously believed that Th1 cells were pathogenic T cells in experimental autoimmune encephalomyelitis (EAE). However, the functional role of Th1 cells in EAE has been reconsidered upon the discovery of IL-17- producing T cells which are consider as dominant effect...

interleukin-17a and interleukin-17f mrna expressions in peripheral blood mononuclear cells of patients with multiple sclerosis

bakground: multiple sclerosis (ms) is a cd4+ t cell-mediated autoimmune disease affecting the central nervous system (cns). it was previously believed that th1 cells were pathogenic t cells in experimental autoimmune encephalomyelitis (eae). however, the functional role of th1 cells in eae has been reconsidered upon the discovery of il-17- producing t cells which are consider as dominant effect...

P 52: Interferon beta-a1 vs. Teriflunomide for Multiple Sclerosis

Multiple sclerosis (MS) is an inflammatory disorder, in which neurons in central nervous system (CNS) become demyelinated .MS is named for its formation of plaques due to sclerosis of myelin. Variable degree of demyelination results in mild, mediate or severe symptomatic episodes of this disease. It is commonly characterized by recurrent relapses and often followed by severe neurological disabi...

Inhibitory effect of the interferon-beta on the release of endothelial cell derived microparticles in patients with multiple sclerosis

Abstract Introduction: Increased levels of microparticles (MPs) have been reported in many autoimmune diseases such as multiple sclerosis (MS). In MS, endothelial cells release MPs from their membranes following the activation of lymphocytes and the production of inflammatory cytokines. The aim of this study was to investigate the inhibitory effect of interferon beta (INFβ) on the release of en...

Interferon beta and suicide in multiple sclerosis.