Interleukin (IL)‐2, IL‐4, and Tumor Necrosis Factor‐α Responses duringEntamoeba histolyticaLiver Abscess Development in Gerbils

Tumor Necrosis Factor-α and Interleukin-1- β Polymorphisms in Pre-Eclampsia

Background: Pre-eclampsia is the most common critical condition during pregnancy. Plasma concentrations of tumor necrosis factor-alpha (TNF-α) and interleukin-1-beta (IL-1β) increase in pregnant women with pre-eclampsia, compared to normal pregnant women. Objective: To investigate the polymorphisms of IL-1β (C+3954T), TNF-α (G- 308A), and (G-238A) in preeclemptic women northeastern Iran. Me...

Interleukin 12, Interferon % and Tumor Necrosis

The Shwartzman reaction is elicited by two injections of lipopolysaccharide (LPS) in mice. The priming LPS injection is given in the footpad, whereas the lethal LPS challenge is given intravenously 24 h later. The injection of interferon 3, (IFN-'y) or interleukin 12 (IL-12) instead of the LPS priming injection induced the lethal reaction in mice further challenged with LPS. Antibodies against ...

Ca 2 + Responses to Interleukin I and Tumor Necrosis Factor in Cultured Human Skin Fibroblasts

Elevated concentrations of cytokines were found in the plasma of patients acutely ill with Reye syndrome (RS) but not in control subjects or recovered RS patients. To determine whether this disorder involves a genetically determined abnormal response to cytokines, the effects of tumor necrosis factor (TNF) and IL-I on intracellular free Ca2" were compared in cultured skin fibroblasts from contr...

CIRCULATING SOLUBLE TUMOR NECROSIS FACTOR RECEPTORS, INTERLEUKIN-2 RECEPTORS, TUMOR NECROSIS FACTOR a, AND INTERLEUKIN-6 LEVELS IN RHEUMATOID ARTHRITIS

Comparison of the expression of interferon gamma, IL2, IL4, and lymphotoxin mRNA in experimental autoimmune uveoretinitis.

The aim of this study was to investigate the T lymphocyte subsets involved in experimental autoimmune uveoretinitis (EAU) by quantifying the numbers of cells expressing mRNA for each of the lymphokines interferon gamma, interleukin 2, interleukin 4, and lymphotoxin throughout the disease process. Lewis rats were immunised with retinal S-antigen to provide a model of inflammatory eye disease. In...