Intermediate: Cognitive phenotypes in bipolar disorder
نویسندگان
چکیده
منابع مشابه
Intermediate: cognitive phenotypes in bipolar disorder.
BACKGROUND Intermediate cognitive phenotypes (ICPs) are measurable and quantifiable states that may be objectively assessed in a standardized method, and can be integrated into association studies, including genetic, biochemical, clinical, and imaging based correlates. The present study used neuropsychological measures as ICPs, with factor scores in executive functioning, attention, memory, fin...
متن کاملCognitive impairment in bipolar disorder.
AIM Provide an overview of how bipolar disorder affects cognitive function in patients. METHODS MEDLINE and PsycInfo data bases were searched for articles indexed by the combinations of MESH term or key word "bipolar disorder" with the following terms: "cognition", "memory", "neuropsychology", "neuropsychological tests", "lithium", "anticonvulsants", "antipsychotics", and "schizophrenia". Con...
متن کاملShared intermediate phenotypes for schizophrenia and bipolar disorder: neuroanatomical features of subtypes distinguished by executive dysfunction.
BACKGROUND Shared genetic vulnerability for schizophrenia and bipolar disorder may be associated with common neuroanatomical features. In view of the evidence for working memory dysfunction as a candidate intermediate phenotype for both disorders, we explored neuroanatomical distinctions between subtypes defined according to working memory (n-back task) performance. METHODS We analyzed T1-wei...
متن کاملOpenness predicts cognitive functioning in bipolar disorder.
OBJECTIVES Openness to experience (O) is a well-established personality factor and is associated with cognitive performance. Little is known about the personality-cognitive relationship in bipolar disorder, an illness with significant variability in mood. Cognitive evaluation is essential in psychopathology assessment as it may reflect underlying disease processes and psychosocial functional ca...
متن کاملCognitive impairment in bipolar II disorder.
BACKGROUND Persistent impairments in neurocognitive function have been described in bipolar disorder. AIMS To compare the cognitive performance of patients with bipolar II disorder with that of patients with bipolar I disorder and a healthy control group. METHOD The study included 71 euthymic patients with bipolar disorder (38 bipolar I, 33 bipolar II), who were compared on clinical and neu...
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ژورنال
عنوان ژورنال: Journal of Affective Disorders
سال: 2010
ISSN: 0165-0327
DOI: 10.1016/j.jad.2009.08.018