Interphase Nuclear Matrix and Metaphase Scaffolding Structures
نویسندگان
چکیده
منابع مشابه
Proteins of metaphase chromosomes and interphase chromatin.
Metaphase chromosomal and interphase chromatin proteins from cells of two species have been compared by polyacrylamide gel electrophoresis. Consistent, common changes in the quantitative distribution of the nonhistone chromosomal proteins are observed in both species. Proteins of ca. 65,000 and 68,000 MW are enriched in interphase chromatin while proteins of ca. 50,000 and 200,000 are more prom...
متن کاملCONTRAST BETWEEN THE ENVIRONMENTAL pH DEPENDENCIES OF PROPHASING AND NUCLEAR MEMBRANE FORMATION IN INTERPHASE-METAPHASE CELLS
In Chinese hamster Don cells, fusion of an interphase cell with a metaphase cell resulted either in prophasing of the interphase nucleus, including loss of the nuclear envelope (NE), or in the formation of a double membrane around the metaphase chromosomes. Only one of these phenomena occurred in a given interphase-metaphase (I-M) binucleate cell. At pH 7.4, there was about an equal probability...
متن کاملInduction of Nuclear Envelopes around Metaphase Chromosomes after Fusion with Interphase Cells
The process of cellular fusion induced by Sendai virus in Chinese hamster cells (Don line) afforded us the opportunity to study nuclear envelope formation around metaphase sets in the presence of interphase nuclei, when chromosome pulverization failed to occur in such multinucleate cells. Morphologically, the enveloped metaphase chromosomes resembled a normal telophase nucleus, though minor dif...
متن کاملAnalysis of aneuploidy in metaphase and interphase cells
Aneuploidy, i.e, changes in the copy number of chromosomes, has a profound impact on the health of the human population. The health consequences range from mental retardation to various neoplasms. A gain or loss of chromosomes can, for example, be induced by radiation. One of the assays for the detection of aneuploidy is the fluorescence in situ hybridization (FISH) technique. Screening by FISH...
متن کاملMetaphase and interphase cytogenetics in fibroadenomas of the breast.
Short-term cultures of fifty-two samples of fibroadenomas were cytogenetically analyzed. Thirty-three of the successfully karyotyped fibroadenomas were further investigated for the presence of amplifications in the CCND1, c-MYC and HER/2-neu genes by means of FISH analysis. Compared to carcinomas, fibroadenomas seem to have less complex cytogenetic rearrangements and limited alterations on HER-...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 1984
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.1984.supplement_1.8