Intravenous caffeine: An alternative to aminophylline to reverse adverse effects during regadenoson myocardial perfusion imaging

Regadenoson for myocardial perfusion imaging: Is it safe?

Regadenoson is currently the most widely used pharmacologic stress agent for myocardial perfusion imaging (MPI) with millions of doses administered annually in the US. In November 2013, the US Food and Drug Administration (FDA) issued a Drug Safety Communication warning health care professionals of the rare but serious risk of heart attack and death with use of either regadenoson or adenosine. ...

Serious complications associated with regadenoson administration for myocardial perfusion imaging

The Editorial by Hage and Iskandrian regarding ‘‘Serious complications associated with regadenoson administration for myocardial perfusion imaging: A commentary’’ (September/October 2014 issue) includes a table as a guide for serious complications associated with regadenoson administration. In the table, the authors reported whether or not each listed event occurs with exercise and/or adenosine...

Determinants of myocardial perfusion reserve measured from coronary sinus phase-contrast imaging during regadenoson stress CMR

Background Measurement of myocardial perfusion reserve (MPR) can potentially extend the scope of conventional myocardial perfusion imaging from detection of flow limiting epicardial stenosis to assessment of coronary microvascular function. Recent studies have suggested that MPR may improve risk stratification of patients with known or suspected CAD. MPR has traditionally been measured using PE...

Regadenoson Cardiac Stress Myocardial Perfusion Scintigraphy

Erythromycin as an alternative to reduce interfering extra-cardiac activity in myocardial perfusion imaging

OBJECTIVES We sought to determine whether taking oral erythromycin prior to SPECT myocardial perfusion imaging with Tc99m-sestamibi would reduce the amount of interfering extra-cardiac activity and improve the image quality. METHODS A total of 96 patients who were routinely referred for myocardial perfusion imaging were randomly assigned to one of two groups. Patients in group A received 500 ...