Intravenous leiomyomatosis: an unusual intermediate between benign and malignant uterine smooth muscle tumors

Uterine smooth-muscle tumors of uncertain malignant potential.

OBJECTIVE To determine whether tumors meeting the criteria of Hendrickson and Kempson for uterine smooth-muscle tumors of uncertain malignant potential have a natural history different from those of leiomyomas and leiomyosarcomas. METHODS Tumors with five to ten mitoses per ten high-power fields and with mild or moderate cellular atypia were classified as tumors of uncertain malignant potenti...

Difference between benign and malignant tumors pdf

Intravenous leiomyomatosis of the uterus with pulmonary metastases or a case with benign metastasizing leiomyoma?

BACKGROUND Intravenous leiomyomatosis (IVL) is defined as an intraluminal growth of benign smooth muscle cells in either venous or lymphatic vessels outside the confines or even in the absence of leiomyomas. Benign metastasizing uterine leiomyoma is defined as a histologically benign uterine smooth muscle tumor that acts in a somewhat malignant fashion and produces benign metastases. We report ...

Frequency of Cytomegalovirus (CMV) in benign and malignant tumors

Cytomegalovirus (CMV) is a widespread pathogen that is found in milk, saliva, urine, cervical secretions, and semen fluid. It is supposed that CMV is a risk factor for breast cancer. The aim of this study was to determine the frequency of CMV among benign and malignant breast tumors. Paraffin embedded breast carcinoma (n=24) and fibroadenoma (n=24) samples were collected from Toos and Firoozgar...

MTA1 Expression in Benign and Malignant Salivary gland Tumors

Introduction: Salivary gland tumors (SGTs) are important parts of human neoplasms. The most common SGT is pleomorphic adenoma and the most common malignant SGTs are mucoepidermoid carcinoma and adenoid cystic carcinoma (ACC). Metastasis-associated genes 1 (MTA1), a member of the nucleosome remodeling and histone deacetylation complex, is one newly discovered gene which recruits histone deacetyl...