Involvement of Different Second Messengers in Parathyroid Hormone- and Interleukin-1-Induced Interleukin-6 and Interleukin-11 Production in Human Bone Marrow Stromal Cells
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منابع مشابه
Wrestlers’ immune cells produce higher interleukin-6 and lower interleukin-12 and interleukin-13 in response toin vitro mitogen activation
Objective(s):Although recent investigations have shown chronic inflammation and inflammation-associated diseases might be ameliorated by exercise; little is known about the relation between exercise training with anti/pro-inflammatory cytokines. Materials and Methods: This cross sectional study was conducted to compare interleukin-4 (IL-4), IL-6, IL-10, IL-12, IL-13, interferon gamma (IFN-γ) le...
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Endothelin (ET) produced by endothelial cells has recently been found to be a potent vasoconstricting hormone. In this report, ET is shown to be a potent stimulator of interleukin-6 (IL-6) production by rat bone marrow (BM)-derived stromal cells. It was also shown that ET increased the level of mRNA for IL-6 in these cells. The two types of ET receptor (R), ETAR and ETBR, were shown to be expre...
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a:4:{s:10:"Background";s:504:"While the etiology of PCOS has continued to remain a mystery, there can be found some evidence in support of the presence of chronic low-grade inflammation in women with this syndrome. One of the most significant manifestations of chronic inflammation is Pro-inflammatory cytokines. Therefore, the aim of this prospective study was to investigate the pattern of proinfla...
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Introduction: Interleukin-2 (IL-2) as a T helper type 1 (Th1) cytokine has an important role Background and Objective: Interleukin-2 (IL-2) as a T helper type 1 (Th1) cytokine has an important role in activation, growth and differentiation of several immune cells. Moreover IL-2 is known as a pro-inflammatory and anti-tumoral cytokine. In addition deysregulation of IL-2 in some diseases such as ...
متن کاملMultiple Myeloma Cell Adhesion-Induced Interleukin-6 Expression in Bone Marrow Stromal Cells Involves Activation
Adhesion of multiple myeloma (MM) cells to bone marrow stromal cells (BMSCsl not only localizes MM cells in the marrow microenvironment, but also triggers interleukin-6 (IL-6) secretion by BMSCs and related MM cell proliferation. In the present study, we characterized the regulation of IL6 gene expression in BMSCs during MM cell adhesion. Adhesion of ARH-77, HS-Sultan, IM-9, and U266 MM cell li...
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ژورنال
عنوان ژورنال: Journal of Bone and Mineral Research
سال: 1997
ISSN: 0884-0431
DOI: 10.1359/jbmr.1997.12.6.896