Is tumour radiosensitization by misonidazole a general phenomenon?
نویسندگان
چکیده
منابع مشابه
HDAC inhibitor-mediated radiosensitization in human carcinoma cells: a general phenomenon?
Histone deacetylase inhibitors (HDIs) have attracted considerable attention for anticancer therapy strategy, including radiosensitization. Regarding a potential application of HDI as a radiosensitizer in the treatment of solid tumors, an important question is whether treatment efficacy would be influenced by intrinsic differences between cancer cells, such as different histologic origin and sta...
متن کاملRadiosensitization of tumour cells by cantharidin and some analogues.
PURPOSE Mammalian cells at mitosis contain chromatin in compacted form and are hypersensitive to ionizing radiation. Previous research had shown some chemicals that induce chromatin compaction within interphase cells act as radiosensitizers. Of these agents, cantharidin (LS-1), which is an inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A), showed good radiosensitizing activity at non-toxi...
متن کاملGeneral Anxiety and Dental Fear: Is There A Relationship?
Introduction: Anxiety is an emotional state that helps healthy people defend themselves against threats. Dental anxiety is referred to a patient's specific response to stressful dental practices. The prevalence of dental anxiety is estimated to be between 3-43%. The relation between dental caries and dental anxiety is well understood, which happen as the result...
متن کاملRadiosensitization by gemcitabine.
Gemcitabine is a potent radiosensitizer in both laboratory studies and in the clinic. Initial laboratory studies showed that gemcitabine radiosensitizes a wide variety of rodent and human tumor cells in culture. Maximum radiosensitization occurs in cells that demonstrate concurrent redistribution into S phase and d-adenosine triphosphate pool depletion. Although the mechanism of sensitization i...
متن کاملExtragonadal germ cell tumour with the "burned out" phenomenon mimicking a retroperitioneal tumour of neurogenic origin.
OBJECTIVE To describe a case of retroperitoneal metastasis of a gonadal germ cell tumour with the "burned-out" phenomenon in a 35 year old patient with a suspected diagnosis of retroperitoneal tumour of neurogenic origin. METHODS With the clinical and radiological suspicion of retroperitoneal tumour of neurogenic origin the tumour was removed, via the retroperitoneal space. RESULTS Patholo...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1980
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1980.1