Joint arterial input function and tracer kinetic parameter estimation from undersampled dynamic contrast‐enhanced MRI using a model consistency constraint
نویسندگان
چکیده
منابع مشابه
Direct estimation of tracer-kinetic parameter maps from highly undersampled brain dynamic contrast enhanced MRI.
PURPOSE The purpose of this work was to develop and evaluate a T1 -weighted dynamic contrast enhanced (DCE) MRI methodology where tracer-kinetic (TK) parameter maps are directly estimated from undersampled (k,t)-space data. THEORY AND METHODS The proposed reconstruction involves solving a nonlinear least squares optimization problem that includes explicit use of a full forward model to conver...
متن کاملBlind estimation of the arterial input function in dynamic contrast-enhanced MRI using purity maximization.
Uncertainty in arterial input function (AIF) estimation is one of the major errors in the quantification of dynamic contrast-enhanced MRI. A blind source separation algorithm was proposed to determine the AIF by selecting the voxel time course with maximum purity, which represents a minimal contamination from partial volume effects. Simulations were performed to assess the partial volume effect...
متن کاملDynamic Contrast-Enhanced MRI of Mouse Liver: A Feasibility Study Using a Dual-Input Two-Compartment Tracer Kinetic Model
Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) has been widely applied to evaluate microcirculatory parameters in clinical settings. However, pre-clinical studies involving DCE-MRI of small animals remain challenging with the requirement for high spatial and temporal resolution for quantitative tracer kinetic analysis. This study illustrates the feasibility of applying a high te...
متن کاملSimultaneous acquisition of dynamic PET-MRI: arterial input function using DSC-MRI and [18F]-FET.
Institute of Neuroscience and Medicine – 4, Forschungszentrum Juelich GmbH, Germany This work focuses on the study of simultaneous dynamic MR-PET acquisition in brain tumour patients. MR-based perfusion-weighted imaging (PWI) and PET [18F]-FET are dynamic methods, which allow to evaluate tumour metabolism in a quantitative way. In both methods, arterial input function (AIF) is necessary for qua...
متن کاملMRI estimation of the arterial input function in mice.
RATIONAL AND OBJECTIVES Dynamic contrast-enhanced (DCE) MRI offers the potential to provide quantitative maps of tumor perfusion parameters and is therefore expected to play an important role in the study of cancer in small animal models. Extraction of such information from DCE-MRI data requires a methodology for determination of the arterial input function (AIF) for the target tissues. An MRI ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Magnetic Resonance in Medicine
سال: 2017
ISSN: 0740-3194,1522-2594
DOI: 10.1002/mrm.26904