l -Arginine and Nitric Oxide: An Inseparable Couple?
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منابع مشابه
L-Arginine supplementation improves antioxidant defenses through L-arginine/nitric oxide pathways in exercised rats.
l-Arginine (l-Arg) supplementation has been shown to enhance physical exercise capacity and delay onset of fatigue. This work investigated the potential beneficial mechanism(s) of l-Arg supplementation by examining its effect on the cellular oxidative and nitrosative stress pathways in the exercised rats. Forty-eight rats were randomly divided into six groups: sedentary control; sedentary contr...
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17 I’egg. A. E. and l’&ii, 11. (1983) Methods Enzyniol. 94,234-239 18 Markhani, G. I). , Tabor. C. W. and Tabor, H. (1983) Methods Enzymol. 94,228-230 10 Hacchi, C. J., Garofalo, J.. Mockenhaupt. I)., McCann, 1’. I]., Iliekema, A.. I’egg, A. E., Nathan, H. C., Mullancy. E. A.. Chunosoff. I,., Sjoerdsma. A. and llutner. S. 11. (1083) Mol. Hiochem. Parasitol. 7, 200-225 20 Yarlett. N. and Hacchi....
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The myeloperoxidase-derived oxidant hypochlorous acid (HOCl) is thought to contribute to endothelial dysfunction, but the mechanisms underlying this inhibitory effect are unknown. The present study tested the hypothesis that HOCl and L-arginine (L-Arg) react to form novel compounds that adversely affect endothelial function by inhibiting nitric oxide (NO) formation. Using spectrophotometric tec...
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متن کاملArginine metabolism: nitric oxide and beyond.
Arginine is one of the most versatile amino acids in animal cells, serving as a precursor for the synthesis not only of proteins but also of nitric oxide, urea, polyamines, proline, glutamate, creatine and agmatine. Of the enzymes that catalyse rate-controlling steps in arginine synthesis and catabolism, argininosuccinate synthase, the two arginase isoenzymes, the three nitric oxide synthase is...
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ژورنال
عنوان ژورنال: Circulation
سال: 2001
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.103.10.e57