l-GLUTAMIC ACID DEHYDROGENASE: STRUCTURAL REQUIREMENTS FOR SUBSTRATE COMPETITION: EFFECT OF THYROXINE
نویسندگان
چکیده
منابع مشابه
Glutamic Acid Dehydrogenase and Glutamic-oxalacetic
As part of a larger project dealing with an in vestigation of amino acid and protein metabolism in leukemia, a study was undertaken to determine those enzymes concerned with amino acid anabo lism and catabolism as they occur in selected tis sues. Several review papers (@,4, 11, 1@)have ade quately summarized our present knowledge of the metabolism of white blood cells (WBC) in leuke mia. Howeve...
متن کاملl-Glutamic acid hydrochloride at 153 K
THE TITLE COMPOUND [SYSTEMATIC NAME: (S)-1,3-dicarboxy-propanaminium chloride], C(5)H(10)NO(4) (+)·Cl(-), has been investigated previously by Dawson [Acta Cryst. (1953). 6, 81-83], with R = 0.106 and without the location of H atoms, and then by Sequeira, Rajagopal & Chidambaram [Acta Cryst. (1972). B28, 2514-2519] using neutron diffraction with R = 0.043. The present determination at 153 K has ...
متن کاملChicken liver glutamic dehydrogenase.
During the course of fractionation of chicken liver extracts, it was observed that glutamic dehydrogenase could be obtained in the crystalline form after a few simple purification steps. The procedure used in the isolation of glutamic dehydrogenase of chicken liver as well as some of the properties of the crystalline enzyme are described in the present communication. Although the chicken liver ...
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The spectrophotometric procedure for determining the specific activity of the enzyme and the preparation of reagents employed in the assay have been described previously (3). DPiV-Commercial preparations of DPN (60 per cent) were used in routine assays. For critical experiments, commercial DPN was further purified by several adsorptions on Dowex 1 formate columns by the method of Kornberg and P...
متن کاملStructural studies on the hydration of L-glutamic acid in solution.
A combination of neutron diffraction augmented with isotopic substitution and computer modeling using empirical potential structure refinement has been used to extract detailed structural information for L-glutamic acid dissolved in 2 M NaOH solution. This work shows that the tetrahedral hydrogen bonding network in water is severely disrupted by the addition of glutamic acid and NaOH, with the ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1957
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)65055-0