Label-free high-speed wide-field imaging of single microtubules using interference reflection microscopy
نویسندگان
چکیده
منابع مشابه
Label-Free Imaging of Single Microtubule Dynamics Using Spatial Light Interference Microscopy.
Due to their diameter, of only 24 nm, single microtubules are extremely challenging to image without the use of extrinsic contrast agents. As a result, fluorescence tagging is the common method to visualize their motility. However, such investigation is limited by photobleaching and phototoxicity. We experimentally demonstrate the capability of combining label-free spatial light interference mi...
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ژورنال
عنوان ژورنال: Journal of Microscopy
سال: 2018
ISSN: 0022-2720
DOI: 10.1111/jmi.12744