Laquinimod Supports Remyelination in Non-Supportive Environments
نویسندگان
چکیده
منابع مشابه
Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis
BACKGROUND Therapeutic strategies that induce effective neuroprotection and enhance intrinsic repair mechanisms are central goals for future treatment of multiple sclerosis (MS), as well as other diseases. Laquinimod (LQ) is an orally administered, central nervous system (CNS)-active immunomodulator with demonstrated efficacy in MS clinical trials and a favorable safety and tolerability profile...
متن کاملCreating Supportive Work Environments for People With Mental Illness
❊ To encourage readers to consider environmental interventions for clients with mental illness who have goals related to work. ❊ To identify key physical, cultural, and institutional aspects of workplace environments that facilitate or hinder clients’ participation in work. ❊ To suggest strategies to create supportive work environments. ❊ To offer a broad conceptualization of work and alternati...
متن کاملHealthy cities as catalysts for caring and supportive environments.
'Caring and Supportive Environments' are fundamental to a social model of health and were a core theme of Phase V (2009-13) of the WHO European Healthy Cities Network. Deploying the methodology of realist evaluation, this article synthesizes qualitative evidence from 112 highly structured case studies from 68 Network cities and 71 responses to a General Evaluation Questionnaire, which asked cit...
متن کاملSupportive and non-supportive interactions in families with a type 2 diabetes patient: an integrative review
BACKGROUND Type 2 diabetes and its management affect the patient and the close family potentially causing either psychological distress or increased sense of responsibility and collaboration in these families. Interactions between patient and family play an important role in maintaining lifestyle changes and diabetes self-management. The purpose of this integrative review was to summarise and a...
متن کاملOral laquinimod therapy in relapsing multiple sclerosis.
BACKGROUND Multiple sclerosis (MS) is a chronic autoimmune disease of the CNS. Early treatment reduces the number of relapses, limits progression of disability, and improves quality of life; however, existing therapies are only partially effective and require parenteral administration. OBJECTIVE To review current experience with laquinimod as a novel immunomodulatory therapy for MS. RESULTS...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cells
سال: 2019
ISSN: 2073-4409
DOI: 10.3390/cells8111363