Latrunculin Analogues with Improved Biological Profiles by “Diverted Total Synthesis”: Preparation, Evaluation, and Computational Analysis
نویسندگان
چکیده
منابع مشابه
Latrunculin analogues with improved biological profiles by "diverted total synthesis": preparation, evaluation, and computational analysis.
Deliberate digression from the blueprint of the total syntheses of latrunculin A (1) and latrunculin B (2) reported in the accompanying paper allowed for the preparation of a focused library of "latrunculin-like" compounds, in which all characteristic structural elements of these macrolides were subject to pertinent molecular editing. Although all previously reported derivatives of 1 and 2 were...
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ژورنال
عنوان ژورنال: Chemistry - A European Journal
سال: 2006
ISSN: 0947-6539
DOI: 10.1002/chem.200601136