Leptin Involvement in Reproductive Performance
نویسندگان
چکیده
منابع مشابه
Role of leptin in human reproductive disorders
Leptin, as a key hormone in energy homeostasis, regulates neuroendocrine function, including reproduction. It has a permissive role in the initiation of puberty and maintenance of the hypothalamic–pituitary–gonadal axis. This is notable in patients with either congenital or acquired leptin deficiency from a state of chronic energy insufficiency. Hypothalamic amenorrhea is the best-studied, with...
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At the international conference on Population and Development held in Cairo 1994, specific aspects of reproductive health addressed endorsed among others, were that unwanted pregnancies must always be given the highest priority and that every attempt should be made to eliminate the need for abortion. This paper focused on the involvement of males in promoting reproductive health through prevent...
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Several studies have recently investigated the role of leptin, the adipocyte-secreted hormone, in the growth and reproduction of rodents, humans, and domestic animals. The present study was designed to explore the expression of leptin and its receptor in pig spermatozoa. Successful Western blot evidenced a 16 kDa band for leptin and six isoforms, ranging from 120 to 40 kDa, for the leptin recep...
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Obesity is associated with an increased risk of breast cancer. Leptin, a hormone synthesised essentially by adipose tissue, may be involved in cancer development. We examined the expression of leptin and leptin receptor (Ob-R) in human primary breast cancer and adjacent non-cancerous tissue. We also analysed their relationships with histological variables such as the oestrogen and progesterone ...
متن کاملPeripheral actions of leptin and its involvement in disease.
The discovery of leptin is broadening our understanding of the mechanisms underlying neuroendocrine function. To date, most investigations have focused on the effects of leptin on food intake control and body weight homeostasis with attention primarily focused on the central effects of leptin. However, the almost ubiquitous distribution of leptin receptors in peripheral tissues provides a ferti...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 1997
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/127.8.1533