Lesion Load May Predict Long-Term Cognitive Dysfunction in Multiple Sclerosis Patients
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چکیده
منابع مشابه
Lesion Load May Predict Long-Term Cognitive Dysfunction in Multiple Sclerosis Patients
BACKGROUND Magnetic Resonance Imaging (MRI) techniques provided evidences into the understanding of cognitive impairment (CIm) in Multiple Sclerosis (MS). OBJECTIVES To investigate the role of white matter (WM) and gray matter (GM) in predicting long-term CIm in a cohort of MS patients. METHODS 303 out of 597 patients participating in a previous multicenter clinical-MRI study were enrolled ...
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In Multiple Sclerosis (MS) prevalence studies of community and clinical samples, indicate that 45-60% of patients are cognitively impaired. These cognitive dysfunctions have been traditionally described as heterogeneous, but more recent studies suggest that there is a specific pattern of MS-related cognitive dysfunctions. With the advent of disease-modifying medications for MS and emphasis on e...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0120754