Ligand-Target Prediction by Structural Network Biology Using nAnnoLyze
نویسندگان
چکیده
منابع مشابه
Ligand-Target Prediction by Structural Network Biology Using nAnnoLyze
Target identification is essential for drug design, drug-drug interaction prediction, dosage adjustment and side effect anticipation. Specifically, the knowledge of structural details is essential for understanding the mode of action of a compound on a target protein. Here, we present nAnnoLyze, a method for target identification that relies on the hypothesis that structurally similar binding s...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2015
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1004157