Light chains in Mediterranean lymphoma.

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Light chains in Mediterranean lymphoma.

Four cases of Mediterranean lymphoma, in two of which serum alpha chains had been identified, were investigated with immunohistochemical techniques. In addition to alpha chains of alpha 1, subclass, monotypic light chains were identified in infiltrating tumour cells in all four patients and in plasma cells in two. The pattern of staining was in keeping with loss of light chain occurring with pl...

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Light chains and the kidney.

Five cases of renal impairment caused by the deposition of light chains in the kidney in association with various immunoproliferative disorders are reported. Light microscopy, immunohistochemistry, and electron microscopy were undertaken and different clinical courses were studied, resulting in variable influences of treatment. Light chain deposition is an important cause of renal impairment an...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1985

ISSN: 0021-9746

DOI: 10.1136/jcp.38.6.601