Light-driven self-assembly of cyanostilbene derivative with reversible chirality in aqueous media

In summary, we presented a design strategy for chiral, amphiphilic, and photoswitchable molecule, using cholesterol, sulfonate, cyanostilbene. The molecule could self-assemble to the trans-isomer in aqueous solution, which is accompanied by strong CD signals. Both trans- cis-isomers are thermally stable, high conversion photoswitching between with good fatigue resistance reversibility, can be achieved different wavelengths of UV irradiation. Furthermore, optical chirality-CD was also modulated According TEM images dynamic light scattering data, process involves self-assembly/disassembly from approximately 150 nm spherical particles 18 irregular particles. We proposed rational light-driven self-assembly molecular photoswitch chirality irradiation media.