“Light” Reading

“Light” Reading

Our knowledge of the crystal structures of two related ligand binding domains (Weber and Steitz, 1987; Su et al., 1995) and a related K ϩ channel pore–forming region (Doyle et al., 1998), together with detailed knowledge of function, makes cyclic nucleotide–gated (CNG) channels a unique model system for studying al-lostery in proteins. Already, we have learned much about the molecular basis for...

Reading Sohrab Sepehri\'s Poetry in Light of Heidegger’s Ontology

As one of the most famous philosophers of the twentieth century, Heidegger has proposed significant ideas about ontology. The undercurrent of his philosophy is the question of being in the world or Dasein. He believes that human is the only creature for whom being in the world is a question and only human is capable of asking about Dasein. Heidegger thinks that authentic poets with their partic...

SubTTS: Light-weight automatic reading of subtitles

We present a simple tool that enables the computer to read subtitles of movies and TV shows aloud. The tool extracts information from subtitle files, which can be freely downloaded or extracted from a DVD, and reads the text aloud through a speech synthesizer. The target audience is people who have trouble reading subtitles while watching a movie, for example people with visual impairments and ...

Commentary “Light” Reading: Targeting Tryptophans in Cyclic Nucleotide–gated Channels

Selected Reading Shedding Uv Light on the Phase Problem

viously very valuable information for structure-based inhibitor design studies. The three-dimensional structure reveals that membrane binding is mediated by a 30 amino acid segment, consisting of two short a helices whose axes are predicted to be approximately parallel to and embedded in the membrane lipid bilayer. Comparison with the structure of the homologous carnitine acetyltransferase (Jog...