Limited Impact of Human Cytomegalovirus Infection in African Infants on Vaccine-Specific Responses Following Diphtheria-Tetanus-Pertussis and Measles Vaccination
Antigen-specific responses to diphtheria-tetanus-acellular pertussis vaccine in human infants are initially Th2 polarized.
Immune responses to exogenous antigens in infant experimental animals display various degrees of Th2 polarization. Preliminary evidence from small human studies suggest a similar age-dependent response pattern to vaccines, but detailed investigations on vaccine immunity during infancy have not yet been undertaken. We report below the results of a comprehensive prospective study on responses to ...متن کامل
Whooping cough and diphtheria are vaccine preventable diseases. Diphtheria, due to Corynebacterium diphtheriae or Corynebactium ulcerans, two Gram positive bacteria, is a serious upper respiratory tract disease with high morbidity and mortality rates. Vaccination, via an acellular vaccine composed only of purified, detoxified diphtheria toxin, has significantly reduced the incidence of the dise...متن کامل
intervals between affected individuals and apparently healthy subjects. Gollob, et al.  proposed a diagnostic criterion for SQTS. SQTS is mostly seen in males and common presentation is aborted SCD (24-32%), arrhythmias and syncope . As the risk of SCD is high in SQTS, ICD placement is strongly recommended for secondary prevention. However, role of ICD in primary prevention is not well de...متن کامل
Impact of maternal postpartum tetanus and diphtheria toxoids and acellular pertussis immunization on infant pertussis infection.
BACKGROUND Mothers often are the source of pertussis illness in young infants. The Centers for Disease Control and Prevention recommend tetanus and diphtheria toxoids and acellular pertussis (Tdap) vaccine for postpartum women before hospital discharge. In January 2008, this recommendation was implemented in a predominantly Hispanic, medically underserved population at Ben Taub General Hospital...متن کامل
short term reactogenicity of a triple diphtheria-tetanus-whole cell pertussis vaccine in iranian infants
background: immunization against diphtheria, tetanus and pertussis (dtp) has long been applied in iran using whole cell vaccine. despite the role of whole cell dtp (dtwp) vaccine in reduction of mortality as a result of disastrous diseases such as diphtheria, tetanus, and pertussis, serious local and systemic complications have been attributed to these vaccines. this study was performed to det...متن کامل
عنوان ژورنال: Frontiers in Immunology