Limonoids Containing a C1–O–C29 Moiety: Isolation, Structural Modification, and Antiviral Activity
نویسندگان
چکیده
منابع مشابه
Synthesis and Antiviral Activity of Novel 1,4-Pentadien-3-one Derivatives Containing a 1,3,4-Thiadiazole Moiety.
1,4-Pentadien-3-one derivatives derived from curcumin possess excellent inhibitory activity against plant viruses. On the basis of this finding, a series of novel 1,4-pentadien-3-one derivatives containing a 1,3,4-thiadiazole moiety were designed and synthesized, and their structures confirmed by IR, ¹H-NMR, and 13C-NMR spectroscopy and elemental analysis. The antiviral activities of the title ...
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Indandione 1 was brominated to yield 2-bromoIndandione 2 which on further reacted with substituted thiocarbamides, carbamides, 2-aminothiophenols, 2-aminophenol and triazoles to furnished 3-substituted aniline-2-thia-4-aza-6,7-benzo-8-oxo-bicyclo [3.3.0]-1(5),3-octadiene 3, 3-substituted aniline-2-oxa-4-aza-6,7-benzo-8-oxo-bicyclo [3.3.0]-1(5),3-octadiene 4, 2-Thia-5-aza-9-oxo-3,4-(3’-substitut...
متن کاملEffects of structural modification of calcium spirulan, a sulfated polysaccharide from Spirulina platensis, on antiviral activity.
Calcium ion binding with the anionic part of a molecule was replaced with various metal cations and their inhibitory effects on the replication of herpes simplex virus type 1 were evaluated. Replacement of calcium ion with sodium and potassium ions maintained the antiviral activity while divalent and trivalent metal cations reduced the activity. Depolymerization of sodium spirulan with hydrogen...
متن کاملSynthesis and Antibacterial Activity of Novel Curcumin Derivatives Containing Heterocyclic Moiety
A series of curcumin derivatives containing heterocyclic moiety have been synthesized and evaluated for their antibacterial activities. The chemical structures of the synthesized compounds were verified on the basis of spectral data and elemental analyses. Investigation of antimicrobial activity of the derivatives demonstrated the ability to inhibit Gram-positive microorganisms with zone of inh...
متن کاملSulfated xylomannans from the red seaweed Sebdenia polydactyla: structural features, chemical modification and antiviral activity.
BACKGROUND Many viruses display affinity for cell surface heparan sulfate proteoglycans with biological relevance in virus entry. This raises the possibility of the application of sulfated polysaccharides in antiviral therapy. METHODS In this study, we analysed polysaccharide fractions isolated from Sebdenia polydactyla. RESULTS The purified xylomannan sulfate and its further sulfated deriv...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2018
ISSN: 1660-3397
DOI: 10.3390/md16110434