Literature review and appraisal on alternative neurotoxicity testing methods
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چکیده
منابع مشابه
Developmental neurotoxicity testing: recommendations for developing alternative methods for the screening and prioritization of chemicals.
Developmental neurotoxicity testing (DNT) is perceived by many stakeholders to be an area in critical need of alternative methods to current animal testing protocols and guidelines. An immediate goal is to develop test methods that are capable of screening large numbers of chemicals. This document provides recommendations for developing alternative DNT approaches that will generate the type of ...
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Toxicity tests are essential for evaluating the safety or hazards of several substances. Many of the current toxicity testing methods include the use of animals, especially rodents. However, in the last three decades, there has been an inclination towards using less animals and performing alternative methods that reduce, refine and replace animal use (3R principle). The viewpoint of “reduction”...
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In Component-Based Software Engineering (CBSE), software systems are mainly constructed with reusable components, such as third-party components and in-house built components. Component Based Software Development (CBSD) is used for making the software applications quickly and rapidly. In Component Based Development (CBD), the software product is built by gathering different components of existi...
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Ceftriaxone is widely used in patients for the treatment of serious gram-negative infections. Ceftriaxone can induce some potential side effects, including neurotoxicity, however, nonconvulsive status epilepticus has rarely been reported. We report a case of acute reversible neurotoxicity associated with ceftriaxone. A 65-yr-old woman with chronic kidney disease developed altered consciousness ...
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ژورنال
عنوان ژورنال: EFSA Supporting Publications
سال: 2018
ISSN: 2397-8325,2397-8325
DOI: 10.2903/sp.efsa.2018.en-1410