Lithium and Not Acetoacetate Influences the Growth of Cells Treated with Lithium Acetoacetate
نویسندگان
چکیده
منابع مشابه
The mechanism of acetoacetate synthesis.
The observation of a coenayme A (CoA)-catalyzed acetoacetate synthesis from acetate and adenosinetriphosphate in pigeon liver extracts (1) grouped this reaction with the larger family of acetylation reactions. Furthermore it furnished partial confirmation of an earlier calculation (2) showing that 16,000 calories are required for the condensation of two acetates to acetoacetate. Thus, one energ...
متن کاملAcetoacetate Formation in Liver
In 1944, Weinhouse et al. (1) reported that the incubation of carboxyllabeled octanoate with rat liver slices yielded acetoacetate in which the carboxyl and carbonyl carbons were equally labeled. Random condensation of 2-carbon units resulting from ,8 oxidation was therefore offered by these workers as a possible mechanism for the formation of acetoacetic acid from octanoate. The conversion of ...
متن کاملAcetoacetate Metabolism in Rat Brain
1. Data are provided that indicate that the rat brain acetoacetyl-CoA deacylase is almost exclusively mitochondrial. Developmental studies show that this enzyme more than doubles its activity during suckling (0-21 days) and then maintains this activity in adults (approx. 1.1 units/g wet wt.). 2. Kinetic studies (on the acetoacetyl-CoA deacylase) in a purified brain mitochondrial preparation giv...
متن کاملWhole cells in enantioselective reduction of benzyl acetoacetate
The β-ketoester benzyl acetoacetate was enantioselectively reduced to benzyl (S)-3-hydroxybutanoate by seven microorganism species. The best result using free cells was obtained with the yeast Hansenula sp., which furnished 97% ee and 85% of conversion within 24 h. After immobilization in calcium alginate spheres, K.marxianus showed to be more stable after 2 cycles of reaction.
متن کاملThe conversion of acetoacetate to pyruvaldehyde.
The ozidative decarboxylation of acetoacetate to pyruvaldehyde is catalyzed by sheep heart extracts in the presence of O2 and Mn*+. The product was identified by spectral and chromatographic methods. From fractionation and inhibitor characteristics and the similarity of the catalytic activity to that of commercial myoglobin, it is concluded that the catalyst for the conversion in sheep heart ex...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2019
ISSN: 1422-0067
DOI: 10.3390/ijms20123104