Long-Term Follow-Up of Children With Congenital Hyperinsulinism on Octreotide Therapy
نویسندگان
چکیده
منابع مشابه
Long-term follow-up of 114 patients with congenital hyperinsulinism.
BACKGROUND The term congenital hyperinsulinism (CHI) comprises a group of different genetic disorders with the common finding of recurrent episodes of hyperinsulinemic hypoglycemia. OBJECTIVE To evaluate the clinical presentation, diagnostic criteria, treatment and long-term follow-up in a large cohort of CHI patients. PATIENTS The data from 114 patients from different hospitals were obtain...
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Congenital chylothorax, defined as the accumulation of lymphatic fluid in the pleural cavity, is a rare neonatal disorder. Nevertheless, congenital chylothorax represents the most common cause of pleural effusion in fetuses and newborns [1]. Due to the rarity of this disorder only a few case series are reported in the literature and current treatment recommendations are based on individual case...
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متن کاملSuccessful treatment of congenital hyperinsulinism with long-acting release octreotide.
CONTEXT Congenital hyperinsulinism (HI) is a common cause of hypoglycemia in infancy. The medical treatment of diazoxide-unresponsive HI is based on a somatostatin analogue. OBJECTIVE This study aims at replacing three daily s.c. octreotide (Sandostatin, Novartis) injections by a single and monthly i.m. injection of long-acting release (LAR) octreotide (Sandostatin LP, Novartis) in HI patient...
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OBJECTIVE Mutations in the KATP channel genes is the most common cause of congenital hyperinsulinism (CHI) of infancy. Our aim was to report the clinical and genetic characteristics, treatment modalities, and long-term prognosis of patients with CHI. METHODS Clinical and biochemical findings, operation procedures, and results of genetic analysis were retrospectively evaluated in 22 CHI patien...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2014
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2014-1866