Loop ileostomyで救命したfulminant <i>Clostridioides difficile</i> colitisの1例(A case of fulminant <i>Clostridioides difficile</i> colitis treated with loop ileostomy)

Acute fulminant pseudomembranous colitis which developed after ileostomy closure and required emergent total colectomy: a case report

INTRODUCTION Pseudomembranous colitis is known to be caused by Clostridium difficile; and, in 3% to 8% of patients, it lapses into an aggressive clinical course that is described as fulminant. We present here a case of extremely rapid and fatal fulminant pseudomembranous colitis that developed after ileostomy closure, a minor surgical procedure. To the best of our knowledge, this is the first c...

Fulminant Ulcerative Colitis

Fulminant ulcerative colitis is a potentially life-threatening disorder that requires expert management to allow for optimal outcomes. Once associated with very high mortality, 1 the medical and surgical treatment of fulminate ulcerative colitis has greatly improved such that mortality from fulminant ulcerative colitis currently is less than 3%. 2 , 3 Optimal management necessitates coordinatio...

Dynamics of mucosal permeability and inflammation in collagenous colitis before, during, and after loop ileostomy.

Collagenous colitis has become a more frequent diagnosis but the aetiology of this disease is still unknown. We describe a female patient with intractable collagenous colitis who was treated with a temporary loop ileostomy. She was followed clinically, histopathologically, and functionally by measuring mucosal permeability before surgery, after ileostomy, and after bowel reconstruction. In our ...

Ileostomy or ileorectal anastomosis for ulcerative colitis?

Fulminant Colitis Following Rituximab Therapy.

Rituximab (RTX; Rituxan, Genentech) is the clinical formulation of a murine immunoglobulin G (IgG) 1 monoclonal anti-CD20 antibody and is widely used in the initial treatment of CD20-positive hematologic malignancies and a variety of autoimmune disorders. Rarely, fulminant colitis has been reported with the use of RTX (Table).1-7 We report a patient who developed 2 episodes of fulminant colitis...