Low-Dose Tissue Plasminogen Activator for Calciphylaxis
نویسندگان
چکیده
منابع مشابه
Low-dose tissue plasminogen activator for calciphylaxis.
A 75-year-old man with end-stage renal disease presented with a 6-month history of nonhealing, markedly painful, necrotic ulcerations of the lower extremities (Figure 1A). The ulceration progressed in spite of multiple treatments elsewhere that included intensive wound care with wet-to-dry dressings, topical becaplermin, surgical debridement, and Unna boot dressings. A skin biopsy specimen demo...
متن کاملThrombolysis with low dose tissue plasminogen activator.
Two cases of vena caval thrombosis in infants were successfully treated with low dose (0.01-0.05 mg/kg/hour) local infusions of tissue plasminogen activator after conventional anticoagulant treatment had been unsuccessful. This approach is useful for clots associated with indwelling intravascular catheters, and a low dose infusion of tissue plasminogen activator as a regional application is rec...
متن کاملLow-dose tissue plasminogen activator and standard-dose tissue plasminogen activator in acute ischemic stroke in Asian populations: a review.
BACKGROUND The burden of stroke is becoming an important issue in Asian countries, where half of the world's population lives. In Western populations, standard-dose intravenous tissue plasminogen activator (tPA) at a dose of 0.9 mg/kg administered up to 4.5 h following acute ischaemic stroke has been shown to improve clinical outcomes. However, the dosage of tPA in Asian populations varies, par...
متن کاملLow-dose tissue plasminogen activator thrombolysis in children.
PURPOSE To compare results of low-dose tissue plasminogen activator (TPA) in children with arterial and venous thrombi relative to standard published dosing. METHODS Subjects consisted of all consecutive children with objectively confirmed thrombi for whom TPA thrombolysis was clinically ordered by the authors. Initial dosing used published standard dose (0.1-0.5 mg/kg per hour). With experie...
متن کاملOptimizing refolding condition for recombinant tissue plasminogen activator
Low molecular size additives such as L-arginine and the redox compounds have been used both in the culturemedium and in vitro refolding to increase recombinant proteins production. Additives increase proteinrefolding and yield of active proteins by suppressing aggregate formation or enhancing refolding process.In this work, a comparative study was performed on refolding of rec...
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ژورنال
عنوان ژورنال: Archives of Dermatology
سال: 2004
ISSN: 0003-987X
DOI: 10.1001/archderm.140.9.1045