Lysosomal hydrolases in calf thyroid

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Lysosomal Acid Hydrolases in Mice Infected with Bcg

Experiments are reported dealing with the increase of lysosomal acid hydrolases induced by BCG infection. Acid hydrolases were determined quantitatively in peritoneal MP, liver homogenate, and plasma of normal and BCG-infected mice. A significant increase of acid phosphatase, beta-glucuronidase, and cathepsin was found in MP and liver homogenate of BCG-infected mice. In plasma also a significan...

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Diagnostic potential of lysosomal hydrolases in body cavity effusions.

Hexosaminidase, alpha-mannosidase, beta-galactosidase, beta-glucuronidase, and arylsulphatase A were measured inperitoneal and pleural effusions from patients with benign, malignant, and inflammatory disorders. Compared with the benign transudates, all enzyme activities were moderately elevated in malignant effusions and markedly elevated in inflammatory effusions. The assay of hexosaminidase a...

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Lysosomal Acid Hydrolases in Mice Infected with Bcg* by Kazuhisa

Infection of laboratory animMs with BCG, an attenuated strain of tubercle bacilli, results in functional changes of the RES x, especially enhanced activity. The heightened phagocytic capacity may well contribute toward resistance of such animals to homologous and heterologous virulent infection (2). One of the consequences of altered activity of the RES induced by infection with BCG is the well...

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Secretion of lysosomal hydrolases by stimulated and nonstimulated macrophages

Peritoneal macrophages were obtained from untreated mice and from mice treated with thioglycollate medium (TA), proteose peptone medium (PP), or a suspension of streptococcus A cell wall material (SA). The biochemical and secretory properties of these cells in long term cultures (up to 2 wk) were compared. TA-elicited macrophages contained more protein, lactate dehydrogenase, lysosomal hydrolas...

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Physicochemical modifications of lysosomal hydrolases during intracellular transport.

1. The following fractions were prepared from rat kidney and characterized ultrastructurally, biochemically and enzymically: (a) an ordinary rough microsomal (RM(1)) fraction; (b) a special rough microsomal (RM(2)) fraction enriched seven- to nine-fold in acid hydrolases over the homogenate; (c) a smooth microsomal (SM) fraction; (d) a Golgi (GM) fraction enriched 2.5-fold in acid hydrolases an...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1966

ISSN: 0006-2936

DOI: 10.1042/bj1000540