Macromolecular Recognition. Formation of Inclusion Complexes of Polymers with Cyclodextrins.
نویسندگان
چکیده
منابع مشابه
Melarsoprol-cyclodextrins inclusion complexes.
Melarsoprol, a water-insoluble drug, is mainly used in the treatment of trypanosomiasis and has demonstrated an in vitro activity on myeloid and lymphoid leukemia derived cell lines. It is marketed as a very poorly tolerated non-aqueous solution (Arsobal). The aim of our work was to develop melarsoprol-cyclodextrin complexes in order to improve the tolerability and the bioavailability of melars...
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glucosyl-ƒ¿-CD (G-ƒ¿-CD), 6-O-ƒ¿-D-glucosyl-ƒÀ-CD (G-ƒÀ-CD), and 6A,6D-di-O-ƒ¿-D-glucosyl-ƒÀ-CD (2G-ƒÀ-CD) with slightly soluble or insoluble drugs in aqueous solution and in the solid state was studied by the solubility method, ultraviolet spectroscopy, and differential scanning calorimetry. These glucosyl-CDs were capable of forming inclusion complexes with compounds which can form complexes ...
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The solubility of trihexyphenidyl (Thp) was improved by its combination with β-cyclodextrin (β-CD) and modified β-CDs. The solubility of Thp was found to be increased in the presence of β-CD, hydroxypropyl-β-cyclodextrin (HP-β-CD), methyl-β-cyclodextrin (Me-β-CD) and sulfobutylether-β-cyclodextrin (SBE-β-CD). In particular, the solubility of Thp in conjunction with SBE-β-CD was increased by a f...
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This study reports the formation of solid vanillin/cyclodextrin inclusion complexes (vanillin/CD ICs) with the aim to enhance the thermal stability and sustained release of vanillin by inclusion complexation. The solid vanillin/CD ICs with three types of CDs (α-CD, β-CD, and γ-CD) were prepared using the freeze-drying method; in addition, a coprecipitation method was also used in the case of γ-...
متن کاملNanostructuring polymers with cyclodextrins
Cristian C. Rusa, Min Wei, Todd A. Bullions, Xintao Shuai, Tamer Uyar and Alan E. Tonelli* Fiber & Polymer Science Program, North Carolina State University, Campus Box 8301, Raleigh, NC 27695-8301, USA Center For High Performance Manufacturing, ESM, Mail Code: 0219, 219 Norris Hall, Virginia Tech, Blacksburg, VA 24061-0219, USA Department of Biomedical Engineering, Case Western Reserve Universi...
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ژورنال
عنوان ژورنال: Proceedings of the Japan Academy, Series B
سال: 1993
ISSN: 0386-2208,1349-2896
DOI: 10.2183/pjab.69.39