Magnetic Nanoparticles and Neurotoxins for Treating Atrial Fibrillation
نویسندگان
چکیده
منابع مشابه
Magnetic nanoparticles and neurotoxins for treating atrial fibrillation: a new way to get burned?
Atrial fibrillation (AF) is the most common cardiac dysrhythmia,1with over 2.6 million Americans affected. Partly due to the high risk of stroke in these patients, AF is associated with significant morbidity and mortality.2 The number of individuals affected with AF is expected to rise 6-fold over the next 40 years. Catheter-based ablation may offer a more effective means of treating AF than co...
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OBJECTIVES We assessed feasibility of magnetic catheter guidance in patients with atrial fibrillation (AF) undergoing circumferential pulmonary vein ablation (CPVA). BACKGROUND No data are available on feasibility of remote navigation for AF ablation. METHODS Forty patients underwent CPVA for symptomatic AF using the NIOBE II remote magnetic system (Stereotaxis Inc., St. Louis, Missouri). A...
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Botulinum neurotoxin (BoNT) A and B are used to treat neuropathic disorders; if retargeted, these agents could be used to treat medical conditions that involve secretion from nonneuronal cells. Here, we report novel strategies for successfully retargeting BoNTs, and also tetanus neurotoxin (TeNT), to primary human blood monocyte-derived macrophages where BoNT/B inhibited the release of tumor ne...
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Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, is an important contributor to population morbidity and mortality. An arrhythmia that is particularly common in the elderly, AF is growing in prevalence with the aging of the population. Our understanding of the basic mechanisms that govern AF occurrence and persistence has been increasing rapidly. This article reviews the ...
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ژورنال
عنوان ژورنال: Circulation
سال: 2010
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.110.000166