Malathion Affects Spermatogenic Proliferation in Mouse
نویسندگان
چکیده
منابع مشابه
PGAM1 is Involved in Spermatogenic Dysfunction and Affects Cell Proliferation, Apoptosis, and Migration.
OBJECTIVE To investigate the correlation between PGAM1 and spermatogenic dysfunction and to evaluate the effect of expression of PGAM1 on the function of germ cells. METHODS Expression of PGAM1 was detected in 40 cases of infertile males with definite pathological diagnosis and 12 cases of mouse models with spermatogenic dysfunction by immunohistochemistry. Then, cell proliferation, apoptosis...
متن کاملLepidium meyenii (Maca) reduces spermatogenic damage induced by a single dose of malathion in mice.
AIM To observe the effect of the aqueous extract of hypocotyls of the plant Lepidium meyenii (Maca) on spermatogenic damage induced by the organophosphate insecticide malathion in mice. METHODS Mice were treated with 80 mg/kg of malathion in the presence or absence of an aqueous extract of Maca, which was orally administered 7, 14 or 21 days after injection of the malathion. Stages of the sem...
متن کاملComputer simulations of the mouse spermatogenic cycle
The spermatogenic cycle describes the periodic development of germ cells in the testicular tissue. The temporal-spatial dynamics of the cycle highlight the unique, complex, and interdependent interaction between germ and somatic cells, and are the key to continual sperm production. Although understanding the spermatogenic cycle has important clinical relevance for male fertility and contracepti...
متن کاملMalathion induces anxiety in the male adult mouse
INTRODUCTION The cholinergic nervous system and acetylcholine esterase are involved in chronic intoxication with organophosphorous insecticides. The present study aims to investigate the influence of the chronic toxicity of these chemicals on behaviors related to anxiety, using the elevated plus maze (EPM), in the male adult mouse. MATERIAL AND METHODS Either water or 1% concentration of mala...
متن کاملA novel class of small RNAs in mouse spermatogenic cells.
Small noncoding RNAs, including small interfering RNAs (siRNAs) and micro RNAs (miRNAs) of approximately 21 nucleotides (nt) in length, have emerged as potent regulators of gene expression at both transcriptional and post-transcriptional levels in diverse organisms. Here we report the identification of a novel class of small RNAs in the mouse male germline termed piwi-interacting RNAs (piRNAs)....
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ژورنال
عنوان ژورنال: International Journal of Morphology
سال: 2012
ISSN: 0717-9502
DOI: 10.4067/s0717-95022012000400023