Mapping the Adenylate Kinase Reaction by Time-Resolved X-ray Solution Scattering

Synchrotron-Based Time-Resolved X-ray Solution Scattering (Liquidography)

Visualizing molecular structures in the course of a reaction process is one of the major grand challenges in chemistry, biology and physics. In particular, most chemical and biologically relevant reactions occur in solution, and solution-phase reactions exhibit rich chemistry due to the solute-solvent interplay. Studying photo-induced reactions in the solution phase offers opportunities for und...

Spatiotemporal kinetics in solution studied by time-resolved X-ray liquidography (solution scattering).

Information about temporally varying molecular structure during chemical processes is crucial for understanding the mechanism and function of a chemical reaction. Using ultrashort optical pulses to trigger a reaction in solution and using time-resolved X-ray diffraction (scattering) to interrogate the structural changes in the molecules, time-resolved X-ray liquidography (TRXL) is a direct tool...

Topical Review: Molecular reaction and solvation visualized by time-resolved X-ray solution scattering: Structure, dynamics, and their solvent dependence

Time-resolved X-ray solution scattering is sensitive to global molecular structure and can track the dynamics of chemical reactions. In this article, we review our recent studies on triiodide ion (I3 (-)) and molecular iodine (I2) in solution. For I3 (-), we elucidated the excitation wavelength-dependent photochemistry and the solvent-dependent ground-state structure. For I2, by combining time-...

Identifying major transient species by combining time- resolved X-ray solution scattering and X-ray absorption spectroscopy

Analysis of time-resolved X-ray scattering data from solution-state systems.

As ultrafast time-resolved studies of liquid systems with the laser pump/X-ray scattering probe method have come of age over the past decade, several groups have developed methods for the analysis of such X-ray scattering data. The present article describes a method developed primarily with a focus on determining structural parameters in the excited states of medium-sized molecules (approximate...