Mature T cell leukemias which cannot be adequately classified under the new WHO classification of lymphoid neoplasms
نویسندگان
چکیده
منابع مشابه
The WHO classification of mature T-cell leukemias.
the mouse models that use randomly integrated trans-genes under transcriptional control of GATA-1 or -globin gene fragments, 9,10 our ErGFP-Cre model uses a defined knock-in strategy to direct fluorescent protein expression to the erythroid lineage. The defined knock-in of a GFP-Cre–encoding transgene into the endogenous erythropoietin receptor (EpoR) gene locus ensures reliable EpoR promoter–...
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In 2008, the World Health Organization (WHO) published a revised and updated edition of the classification of tumors of the hematopoietic and lymphoid tissues. The aims of the fourth edition of the WHO classification was to incorporate new scientific and clinical information in order to refine diagnostic criteria for previously described neoplasms and to introduce newly recognized disease entit...
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The current World Health Organization (WHO) classification of hematopoietic malignancies defines several types of mature T-cell leukemia including T-cell prolymphocytic leukemia (T-PLL), Sezary syndrome (SS), and T-cell large granular lymphocytic (T-LGL) leukemia. These neoplasms can show overlapping features with each other and with T-cell lymphomas involving peripheral blood (PB). We analyzed...
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We identified a new human, T-lineage restricted glycoprotein of molecular weight 120 Kd that is expressed primarily in mature T-cell malignancies. The antigen, named TCA-1 (T-cell cytoplasmic antigen), is an intracellular glycoprotein found mainly in the Golgi stacks, although a few cell lines also display surface membrane TCA-1. Many but not all T-cell neoplasms express this antigen. The antig...
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For the classification of chronic lymphoid leukemias (CLL) the first decision made by the French-American-British (FAB) Cooperative Leukemia Study group (Fig 1) was to employ flow cytometry to separate CLL into two broad categories: B-CLL and T-CLL (1). It was recognized that certain cytomorphologic features were so strongly associated with a specific diagnosis that markers were of minor intere...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2002
ISSN: 0887-6924,1476-5551
DOI: 10.1038/sj.leu.2402715