Maximizing genetic gain over multiple generations with quantitative trait locus selection and control of inbreeding1
نویسندگان
چکیده
منابع مشابه
Maximizing genetic gain over multiple generations with quantitative trait locus selection and control of inbreeding.
Stochastic computer simulation was used to investigate the potential extra genetic gains obtained from gene-assisted selection (GAS) by combining 1) optimization of genetic contributions for maximizing gain, while restricting the rate of inbreeding with 2) optimization of the relative emphasis given to the QTL over generations. The genetic model assumed implied a mixed inheritance model in whic...
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We present in this paper models and statistical methods for performing multiple trait analysis on mapping quantitative trait loci (QTL) based on the composite interval mapping method. By taking into account the correlated structure of multiple traits, this joint analysis has several advantages, compared with separate analyses, for mapping QTL, including the expected improvement on the statistic...
متن کاملQuantitative trait locus analysis.
Alcoholism is a quantitative disorder that is caused by the combined influences of numerous genes (i.e., quantitative trait loci [QTLs]) and environmental factors. To identify QTLs for alcoholism, researchers compare subject groups (e.g., inbred mouse strains) that differ in both their genetic makeup (i.e., genotype) and alcohol-related trait (e.g., sensitivity to certain alcohol effects). Usin...
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ژورنال
عنوان ژورنال: Journal of Animal Science
سال: 2004
ISSN: 0021-8812,1525-3163
DOI: 10.2527/2004.8251305x