Measurement of Protoporphyrin and Zinc Protoporphyrin in Lead Worker Erythrocytes Using HPLC
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چکیده
منابع مشابه
Light-induced release of protoporphyrin, but not of zinc protoporphyrin, from erythrocytes in a patient with greatly elevated erythrocyte protoporphyrin.
A patient with greatly increased erythrocyte protoporphyrin, but normal porphyrins in urine and feces, is described. The patient later developed a malignant lymphoma, and the reason why she accumulated protoporphyrin in her erythrocytes is not known. The protoporphyrin in the erythrocytes consisted of two types of protoporphyrin, free protoporphyrin (30%) and zinc protoporphyrin (70%). Upon irr...
متن کاملLead, hemoglobin, zinc protoporphyrin and ferritin concentrations in children.
OBJECTIVE To assess the relationship of blood lead and hemoglobin, zinc protoporphyrin, and ferritin concentrations in children. METHODS A cross-sectional study was carried out in 136 anemic and non-anemic children from two rural villages near a lead smelter in Adrianópolis, Southern Brazil, from July to September 2001. Hemoglobin electrophoresis was performed to exclude children with hemoglo...
متن کاملHemoglobin, serum iron, and zinc protoporphyrin in lead-exposed workers.
In a previous study of secondary lead smelter workers (males), a significant prevalence of low hemoglobin levels (less than 14 g/100 ml) was found; a statistically significant negative correlation between hemoglobin and zinc protoporphyrin was also detected. In the present study serum iron (Fe) levels and total iron binding capacity (TIBC) were included in the investigation of 111 secondary lea...
متن کاملEFFECT OF CHRONIC LEAD POISONING ON ERYTHROCYTE PROTOPORPHYRIN IN RATS
Research has shown that exposure to lead may have adverse effects at different blood lead concentrations. Lead inhibits at least two enzymes that are essential for the formation of heme, and because of the interaction of lead with these enzymes, no iron is inserted into protoporphyrin. Therefore the concentration of protoporphyrin increases in erythrocytes. The concentration of lead was mea...
متن کاملLight - Induced Release of Protoporphyrin , But Not of Zinc Protoporphyrin , From Erythrocytes in a Patient With Greatly Elevated Erythrocyte
A patient with greatly increased erythrocyte protoporphyrin, but normal porphyrins in urine and feces. is described. The patient later developed a malignant lymphoma. and the reason why she accumulated protoporphyrin in her erythrocytes is not known. The protoporphyrin in the erythrocytes consisted of two types of protoporphyrin. free protoporphyrin (30%) and zinc protoporphyrin (70%). Upon irr...
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ژورنال
عنوان ژورنال: Sangyo Igaku
سال: 1981
ISSN: 0047-1879,1881-1302
DOI: 10.1539/joh1959.23.7_747_1