Mechanical and geometrical study of 3D printed Voronoi scaffold design for large bone defects

The Voronoi design was utilized for a biodegradable patient-specific bone scaffold with macro pores (>4 mm) the surgical treatment of critical-sized defect. We have focused on relationship between and mechanical properties. Through combination experiments simulations presented morphological property maps designs based tessellation. Fused filament fabrication (FFF) explored as method prototypes were printed in commercial grade Polylactic Acid (PLA). subsequent in-silico morphology assessment revealed that pore sizes ranged from 4.0 to 11.8 mm total porosity 71%. capture distinct geometry shift as-designed as-manufactured scaffolds an average agreement 76% where most deviations caused by complications innate 3D printing. Finite element models developed evaluate properties failure locations accurately predicted, which validated quasi-static compression test. This study potential tessellation patient specific mimic trabecular concluded FFF is suitable it.