Mechanical efficiency of stunned myocardium is modulated by increased afterload dependency
نویسندگان
چکیده
منابع مشابه
Selective enhancement of function of stunned myocardium by increased flow.
Although augmentation of flow does not improve the performance of normal myocardium, the hyperemic response after brief coronary occlusion is associated with transient hyperfunction in the previously ischemic region. In this study we assessed the effect of vasodilator-enhanced coronary blood flow on the systolic function of postischemic stunned myocardium. In 18 open-chest, anesthetized dogs th...
متن کاملIncreased Oxygen Cost of Contractilit in Stunned Myocardium of Dog
Recent studies have shown that myocardial oxygen consumption does not proportionally decrease with the deterioration of contractile function in stunned myocardium. To investigate this disproportion, we studied the end-systolic pressure-volume relation and the relation between oxygen consumption per beat (Vo2) and systolic pressure-volume area (PVA, a measure of total mechanical energy) in stunn...
متن کاملIncreased oxygen cost of contractility in stunned myocardium of dog.
Recent studies have shown that myocardial oxygen consumption does not proportionally decrease with the deterioration of contractile function in stunned myocardium. To investigate this disproportion, we studied the end-systolic pressure-volume relation and the relation between oxygen consumption per beat (VO2) and systolic pressure-volume area (PVA, a measure of total mechanical energy) in stunn...
متن کاملStunned Myocardium of Dog
Recent studies have shown that myocardial oxygen consumption does not proportionally decrease with the deterioration of contractile function in stunned myocardium. To investigate this disproportion, we studied the end-systolic pressure-volume relation and the relation between oxygen consumption per beat (Vo2) and systolic pressure-volume area (PVA, a measure of total mechanical energy) in stunn...
متن کاملIncreased cross-bridge cycling rate in stunned myocardium.
Decreased Ca2+ responsiveness of the myofilaments underlies myocardial stunning. Given that cross-bridge cycling is a major determinant of myofilament behavior, we quantified cross-bridge cycling rate in stunned myocardium. After stabilization, rat hearts were subjected to 20 min of no-flow global ischemia and 30 min of reperfusion at 37 degrees C. Control hearts were perfused continuously at 3...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 1995
ISSN: 0008-6363
DOI: 10.1016/0008-6363(96)88602-0