MeCP2 Expression in a Rat Model of Risky Decision Making
نویسندگان
چکیده
منابع مشابه
Sex differences in a rat model of risky decision making.
Many debilitating psychiatric conditions, including drug addiction, are characterized by poor decision making and maladaptive risk-taking. Recent research has begun to probe this relationship to determine how brain mechanisms mediating risk-taking become compromised after chronic drug use. Currently, however, the majority of work in this field has used male subjects. Given the well-established ...
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Risky decision-making is characteristic of depression and of addictive disorders, including pathological gambling. However it is not clear whether a propensity to risky choices predisposes to depressive symptoms or whether the converse is the case. Here we tested the hypothesis that rats showing risky decision-making in a rat gambling task (rGT) would be more prone to depressive-like behaviour ...
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In this report, we analyze adolescent risk-taking from a behavioral decision-making perspective, with respect to the following questions: •Why is adolescent risky decision making important? •What is rational, adaptive, or good decision-making for adolescents (i.e., normative approaches)? •What are the main explanatory models of adolescent risk taking? •What are the key data (i.e., those data th...
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Are people willing to gamble more for themselves than what they deem reasonable for others? We addressed this question in a simplified computer gambling task in which subjects chose from a set of 10 cards. Subjects selected one card at a time after being instructed that 9 cards were good (win a dollar per card) and one was really bad (lose all the money and end the game). Subjects could stop pl...
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Some people love taking risks, while others avoid gambles at all costs. The neural mechanisms underlying individual variation in preference for risky or certain outcomes, however, remain poorly understood. Although behavioral pathologies associated with compulsive gambling, addiction and other psychiatric disorders implicate deficient serotonin signaling in pathological decision making, there i...
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ژورنال
عنوان ژورنال: Neuroscience
سال: 2018
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2017.11.016