Medical algorithm: Diagnosis and treatment of eosinophilic esophagitis in children

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Diagnosis and treatment of eosinophilic esophagitis

Eosinophilic esophagitis (EoE) is a new disease. It is caused by a T-helper type 2 cell response to food antigens in contact with the esophageal mucosa. Although no single feature defines EoE, a constellation of compatible demographic, clinical, endoscopic, and histologic findings establish the diagnosis. Children present with symptoms and endoscopic patterns characteristic of inflammation, whe...

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Eosinophilic esophagitis -- clinical manifestations, diagnosis, and treatment.

Eosinophilic esophagitis (EE) is a chronic inflammatory, immunoallergic disease of the esophagus that represents the most common eosinophilic gut disease. Understanding and diagnosis regarding this condition have greatly increased in recent years, particularly in Europe and North America, in parallel with other allergic disorders. It consists of dense esophageal infiltration with eosinophils in...

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Diagnosis and management of eosinophilic esophagitis in children.

QUESTION After a few years of difficulty swallowing solids and feeling like food was getting stuck, a 13-year-old boy in my practice with peanut allergy and asthma was recently diagnosed with eosinophilic esophagitis (EoE). What is EoE and how is it diagnosed and managed? ANSWER Eosinophilic esophagitis is an immune-mediated disease resulting in inflammation of the esophagus. It is increasing...

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Eosinophilic esophagitis in children: a pathologic or clinicopathologic diagnosis?

OBJECTIVE To determine the accuracy of histopathologic diagnosis in distinguishing eosinophilic esophagitis (EE) from gastroesophageal reflux disease (GERD) in children with upper aerodigestive symptoms. DESIGN Masked review of esophageal biopsy findings and comparison with each child's established clinical diagnosis. SETTING A tertiary care multidisciplinary aerodigestive center. PATIENT...

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ژورنال

عنوان ژورنال: Allergy

سال: 2020

ISSN: 0105-4538,1398-9995

DOI: 10.1111/all.14188