Membrane rafts in host–pathogen interactions
نویسندگان
چکیده
منابع مشابه
Lipid rafts and membrane dynamics.
Cell membranes contain a variety of lipid species that differ in their physico-chemical properties. Lipid-lipid immiscibility gives rise to lateral heterogeneities in the membrane plane, a subset of which are termed lipid rafts (Simons and Vaz, 2004). Originally defined biochemically as detergentresistant membrane (DRM) fractions, lipid rafts are proposed to be highly dynamic, submicroscopic as...
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Cell membranes are composed of a lipid bilayer, containing proteins that span the bilayer and/or interact with the lipids on either side of the two leaflets. Although recent advances in lipid analytics show that membranes in eukaryotic cells contain hundreds of different lipid species, the function of this lipid diversity remains enigmatic. The basic structure of cell membranes is the lipid bil...
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Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, steroland sphingolipid-enriched domains that compartmentalize cellular processes. Many studies have established that membrane rafts play an important role in the process of virus infection cycle and virus-associated diseases. It is well known that many viral components or virus receptors are concentrated in the lipid microdoma...
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In order to study the molecular characteristics of an integral membrane protein, first the protein should be solubilized. Ascorbate-reducible b-type cytochromes are highly hydrophobic integral membrane proteins with six trans-membrane α-helices. A fully ascorbatereducible b-type cytochrome was easily solubilized by Triton X-100 from phase partitionpurified plasma membranes of 5-day-old etiolate...
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The sphingolipids comprise a complex range of lipids in which fatty acids are linked via amide bonds to a long-chain base or sphingoid. The root term “sphingo-” was first coined by J.L.W. Thudichum in 1884 because the enigmatic nature of the molecules reminded him of the riddle of the sphinx. The term “sphingolipide” was introduced by Herbert Carter and colleagues in 1947. While they are perhap...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 2006
ISSN: 0005-2736
DOI: 10.1016/j.bbamem.2006.07.017